Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System

by Andrew G. Mtewa PhD MSc B.Ed (Editor), Tadele Mekuriya PhD fellow MSc B.Sc (Editor)

Cannabis and Khat in Drug Discovery: The Discovery Pipeline and the Endocannabinoid System provides comprehensive coverage of two important psychoactive plants: Khat and Cannabis. Initial research has found that compounds and derivatives from Cannabis and Khat are found to have promising properties that can be used for the discovery, design and development of potential drug leads against various diseases. This book extensively discusses the drug discovery and allied sciences of these compounds in the drug discovery pipeline, including basic research and computer aided modeling in ligand-drug interactions and their interactions with the endocannabinoid system. Categorized into sections including, chemical analyses and bioassays, medicinal chemistry, chemical biology and pharmacology, clinical applications, and policy and regulations, this book covers the methods and protocols involved and will be of interest to students, researchers, policymakers and all those involved in drug discovery research.

• Covers the medicinal chemistry, pharmacology and biological chemistry of cannabis, khat, their constituent compounds and metabolites
• Presents both the adverse and the beneficial entities to health and drug discovery
• Includes detailed methods and protocol information to allow easy replication and application