Lung Biology and Pathophysiology
Description
(Methods in Signal Transduction Series)
Yutong Zhao
ISBNs: B0CRC9SSQR, 1032409029, 9781032409023, 978-1-032-40902-3,
9781032409023, 978-1-032-40906-1, 978-1032409061, 9781032409061,
978-1-003-35524-3, 9781003355243, 978-1003355243
English | 2024 | PDF | 291 Pages
The lungs are the organ for gas exchange between the body and the
external environment. Dysfunction of upper airway epithelium and smooth
muscle cells leads to pathogenesis of asthma, chronic obstructive
pulmonary disease (COPD), cystic fibrosis, and other conditions,
resulting in airway inflammation and narrowing. Injury to alveolar
epithelium and endothelium causes influx of neutrophil and protein-rich
fluid from circulation, resulting in edema and disruption of gas
exchange. In addition to lung structural cells, immune cells, including
alveolar macrophages and lymphocytes play critical roles in the
maintenance of lung function. This book contributes to the understanding
homeostasis of lung cells in the physiological and pathological
conditions critical to the development of novel therapeutics.
Key Features
Highlights the role the lungs play as an interface between the body and the environment
Describes the underlying mechanism of lung diseases
Emphasizes the ways nutrition contributes to lung health as well as the ways pollution adversely affect lung function
Includes contributions from leading researchers
